Peyronie’s Disease in Cincinnati.

Abnormal angulation (or bent) penis

Peyronie’s Disease in Cincinnati

What is Peyronie’s Disease?

Peyronie’s disease is a curvature of the penis caused by scar tissue on one side of the penis. This condition can affect a man at any age.

What causes Peyronie’s?

The cause of Peyronie’s is unknown. Trauma to the penis, which may cause internal bleeding and scar (or plaque) formation is the most common cause; however, the trauma can be very mild and go unnoticed at the time. Other theories involve a genetic risk.

What are the symptoms of Peyronie’s?

When the penis is erect, the hardened plaque will cause the penis to bend or curve. This curvature can cause pain and interfere with a man’s ability to have sexual intercourse.

How do I treat Peyronie’s?

Up until this point, there were very few effective treatment options for Peyronie’s Disease. Medications have been tried, both orally (Pentoxifylline) and injected directly into the plaque (Verapamil or Xiaflex), which do not tend to be very effective, and pose risk for penile fracture. A final option is surgery to remove the plaque or surgery to alter the tissue on the opposite side of the penis, called the Nesbit procedure. Side effects of these treatments include issues with erectile dysfunction and shortening of the penis.

Thankfully,  alternative treatment options, that are free from the side effects from drugs or surgery, are now available called the P-Shot® (Priapus Shot®) and Himtensity Wave Therapy.


What is the P-shot® and how does it treat Peyronie’s?

The P-Shot® involves injecting PRP, or platelet rich plasma, both into the shaft of the penis and directly into the penile plaque, or area of scan that cause the penis to bend. A small amount of blood is drawn from the arm. Using a centrifuge, the physician isolates platelets from that blood (platelet rich plasma, or PRP), all within about 15 minutes in the office. Activation of the PRP results in release of at least 8 different growth factors that would normally be used to heal injured tissue. These growth facts work like magic go increase collagen and elastin, promote angiogenesis (or the formation of new blood vessels), improve blood flow and break down the hardened plaque causing the curvature. Over 7,000 papers have been published speaking to the efficacy of PRP in healing tissue.

Added benefits of PRP in the form of the Priapus Shot® include:

  • Increased size of penis
  • Straightened penis
  • Increased blood flow to the penis for improved erections
  • Additional therapies like Viagra® or Cialis® work better
  • Increased sensation and pleasure

There is zero down time after a P-shot. Other than potential tenderness at the injection site, there are virtually no adverse effects or side effects of the P shot.

What is Himtensity Wave Therapy?

Himtensity Wave Therapy for Peyronie’s is a non-invasive treatment involving the use of acoustic waves that are delivered to the affected area. These waves help promote tissue healing and regeneration by increasing blood flow, stimulating the production of new blood vessels, and breaking down scar tissue. By targeting the fibrous plaques that cause penile curvature and erectile dysfunction in Peyronie’s disease, wave therapy aims to improve penile function and reduce symptoms. Himtensity is a zero downtime procedure.

What is Himtensity? Listen to the 5 minute podcast with Dr. Amy Brenner

Dr. Brenner offers a brief overview of how Himtensity works. Continued…

Listen Here 


We have worked with urologists across the country to develop a treatment protocol to address all aspects of Peyronie’s Disease in Cincinnati, as well as maximize success of therapy through a comprehensive approach. Our treatment protocol consists of:

  • P-Shots®, spaced 8 weeks apart
  • Specific supplements to promote healthy blood vessels and blood flow
  • Himtensity Wave Therapy

How do I schedule an evaluation to see if I am a candidate for the procedure(s)?

Your initial consultation with one of our physicians will begin with a thorough look into your past medical and surgical history, family history, and current medications, with specific attention paid to factors influencing success of the procedure. Our experts utilize the Sexual Health Inventory for Men (SHIM) score—a validated questionnaire that assesses erectile function. This allows us to better understand your specific situation and design a personalized approach just for you.

After deciding together if you are a candidate, your provider will customize a treatment plan that addresses your concerns.

Schedule a Consultation

It's simple— identify the problem areas of your body and we will recommend the right treatment plan for you.

Schedule In-Person Consultation Virtual Consultation