Dr. Brenner sitting down and talking to a patient

Peptide Therapy.

Am I a Candidate?

Peptide Therapy in Cincinnati, Ohio

Targeted Wellness Treatments

Peptide therapy is a way to reduce the symptoms for a wide variety of conditions.  The use of specific peptides in treatment, has gained great popularity in recent years, due largely to the fact that peptides are highly specific (i.e., only do what you want them to do) while also being well-tolerated and safe.

They can be used as a stand-alone treatment; however, peptides work best when multiple peptides are used as part of an overall treatment plan encompassing hormone optimization, gut health, stress response/cortisol, exercise and diet.

Our providers can work with you on a comprehensive treatment plan to optimize your body composition, sexual health, overall well-being and beyond.

What is Peptide Therapy?

A peptide is a short chain of amino acids that are linked together and can be thought of as a small protein. To date, over 7,000 naturally-occurring peptides have been identified.

In our bodies, these small proteins typically act as signaling molecules. They bind to receptors on the cell surface and tell other cells and molecules what to do.

Most of these peptide drugs are administered via subcutaneous injections, but can also come in the form of transdermal creams, nasal sprays, and oral tablets.

Would you benefit from Peptide Therapy?

Peptide therapy encompasses numerous different drugs with varied effects, ranging from immune support and tissue repair to fat loss and muscle building. The therapeutic benefits of peptides will depend on the protocol you follow and the goals you wish to achieve. Peptide protocol and combinations are individualized to each person.

Some benefits of peptides include:

  • Muscle building
  • Immune support
  • Sexual health
  • Weight loss
  • Improved memory
  • Improved learning and focus
  • Sleep improvement
  • Improved mitochondrial function
  • Cellular repair and regeneration
  • Improved endurance and athletic capability

 

What conditions do peptide therapy address?

 At Amy Brenner MD & Associates, we break down what peptides can address into these categories:

Athletic Performance and Body Composition

Sermorelin
  • Increases muscle growth
  • Increases fat loss
  • Promotes slow wave deep sleep
Tesamorelin and Ipamorelin Combination
  • Increases muscle growth
  • Increases fat loss
  • Reduces triglyceride levels
5-Amino 1MQ
  • Improves endurance
  • Improved muscular strength
  • Promotes weight loss
Brain Health and Memory

Selank

  • Helps with memory and learning
  • Reduces effects of chronic stress
  • Multiple wellness benefits
Semax
  • Improves cognition and focus
  • Helps with memory and learning
  • Multiple wellness benefits
Sermorelin
  • Promotes memory retention
  • Increases cellular repair
  • Multiple wellness benefits
Immunity
BPC 157
  • Increases cellular repair and regeneration
  • Promotes healing
Inflammation
BPC 157
  • Anti-Inflammatory
  • Promotes repair, regeneration & healing
Insulin Resistance
Semaglutide
  • Reduces sugar cravings
  • Promotes weight loss
  • Improves HbA1C
Mitochondrial Health
5-Amino 1MQ
  • Improves energy
  • Improves neurologic dysfunction
Rapamycin
  • Improves cell health
  • Boosts immune system
Mood and Stress

Selank

  • Enhances mood
  • Reduces anxiety
  • Reduces effects of chronic stress
Semax
  • Improves mood and focus
  • Boosts confidence and well-being
Epitalon
  • Improves stress
  • Improves sleep
Pain Management
BPC 157
  • Increases cellular repair and regeneration
  • Promotes healing
Sexual Wellness

 

PT-141
  • Libido
  • Sexual satisfaction
  • Erectile dysfunction
  • Sexual arousal disorder
Oxytocin
  • Sexual quality
  • Mood
Melanotan
  • Libido
Sleep

Delta Sleep Inducing (DSIP)

  • Promotes deep sleep and repairs circadian rhythm
  • Improves sleep patterns

Sermorelin

  • Promotes slow wave deep sleep
  • Multiple wellness benefits
Oxytocin
  • Sleep promoting
  • Improves mood
Weight Loss
5-Amino 1MQ
  • Promotes weight loss
  • Improves endurance
Sermorelin
  • Increased muscle growth
  • Increased fat loss
  • Increased cellular repair and regeneration
  • Increased collagen production(better skin)
  • Promotes slow wave deep sleep for muscle recovery
Semaglutide
  • Reduces appetite
  • Promotes weight loss
  • Reduces sugar cravings
Tesofensine
  • Suppresses appetite
  • Promotes weight loss

5 Amino 1MQ

5-amino 1MQ has been used to improve body composition, promote fat loss and muscle gain.  5-amino 1MQ works by blocking NNMT (nicotinamide N-methyltransferase) to enhance fat cell metabolism and promote weight loss. Most people don’t know that NNMT has been implicated in a number of other diseases including metabolic disorders, cardiovascular disease,  Parkinson’s disease, kidney disease, and other neurovascular/neurological dysfunctions.

Potential Benefits:

  • Promotes weight loss (in combination w/ diet & exercise)
  • Improved endurance
  • Improved muscular strength
  • Can prevent lipogenesis
  • Improved energy
  • Improved neurologic dysfunction
  • Support cardiovascular health
  • Support kidney health

Potential Side Effects

  • Hives
  • Possible Allergic Reaction

Contradictions:

  • Pregnancy and breastfeeding

Pairs well with:

Sermorelin, NAD+ Therapy, Tesofensine, AB Modern Day Warrior Program (Semaglutide)

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BPC 157 Peptide

BPC stands for “Body Protection Compound” and is found in human gastric juice. This peptide has been shown to help with healing and repairs, it achieves this through the regulation of growth factors that help make bone, cartilage and tissue.  BPC promotes a faster healing process to gain recovery in less time.

Potential Benefits:

  • Heal digestive system, leaky gut, chronic constipation
  • Promote repair of the tendon, ligaments, muscle, bone, intestine, and nervous system
  • Promote, ligament, tendon and wound healing
  • Increased cellular repair and regeneration
  • Increased collagen production
  • Anti-inflammatory

Potential Side Effects:

  • Hives (allergic reaction)

Contradictions:

  • Pregnancy and breastfeeding

Pairs well with:

Thymosin Alpha 1 and Thymosin Beta 4

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Sermorelin

Sermorlin is the latest in growth hormone peptide combinations. Benefits include longer binding time to growth hormone receptors, no risk of receptor saturation, none of the side effects of earlier peptides, and a strong safety & efficacy profile.

Potential Benefits:

  • Increase muscle growth
  • Increase fat loss
  • Increase cellular repair and regeneration
  • Increased collagen production
  • Increased bone mineral content
  • Promotes slow wave deep sleep which is responsible for the highest level of muscle growth and memory retention and rejuvenation

Potential Side Effects:

  • Hives
  • Redness at injection side
  • Vivid dreams
  • Difficulty sleeping (switch to a.m. dose)
  • Flushing in about 30% of patients w/first injection, could be every time

Contradictions:

  • Pregnancy and breastfeeding
  • Patients with a history of any form of cancer

Pairs well with:  Tesofensine, 5 Amino 1MQ, Tesamorelin 

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Delta Sleep Inducing - DSIP

Delta Sleep Inducing Peptide (DSIP) has shown to help with promoting deep sleep and repairing circadian rhythms.

Potential Benefits:

  • Promotes deep sleep including in chronic insomnias
  • Improves sleep patterns
  • Promotes repair to circadian rhythms
  • May help to combat withdrawal symptoms from chronic use of sleeping pills

Potential Side Effects:

  • Hives (allergic reactions)

Contradictions:

  • Pregnancy and breastfeeding

Pairs well with:

Sermorelin

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Epitalon

Epitalon increases the natural production of telomerase, a natural enzyme that helps cells reproduce telomeres, which are the protective parts of our DNA. This allows the replication of our DNA so the body can grow new cells and rejuvenate old ones.

Potential Benefits:

  • Improves cholesterol
  • Improves sleep
  • HPA Axis Reset
  • Improves stress response
  • Boosts energy
  • Improves muscle recovery and damage
  • May lengthen telomeres

Potential Side Effects:

  • Hives (allergic reactions)

Contradictions:

  • Pregnancy or Breastfeeding

Pairs well with:

Selank

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Melanotan Peptide

Melanotan helps body composition, increases pigmentation (tanning effect) and can also increase libido.

Potential Benefits:

  • Increase in libido
  • Increase in lipid & glucose regulation
  • Increased pigmentation of skin tone
  • Decreases oxidative stress
  • Increased immunity
  • Enhances thermogenic response

Potential Side Effects

  • Hives
  • Possible Allergic Reaction
  • Nausea or vomiting
  • Yawning
  • Delayed onset erection
  • Can temporarily increase blood pressure post injection

Contradictions:

  • Pregnancy or breastfeeding

Melanotan will not be prescribed for patients with a history of any form of skin cancer or with uncontrolled blood pressure.

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Oxytocin

Oxytocin has been called the “love hormone” as its responsible for some of the positive emotions we feel during sexual arousal and orgasm.  Studies suggest Oxytocin may also promote sleep by countering the effects of cortisol (stress). Increased levels of this naturally occurring hormone may help with a variety of symptoms.

Potential Benefits:

  • Increased satisfaction with quality of sex life
  • Improves mood
  • Improves communication
  • Promotes a feeling of empathy and trust
  • Reduces sugar cravings

Potential Side Effects:

  • Hives (allergic reaction)
  • Headache, dizziness

Contradictions:

    • Pregnancy and breastfeeding
    • Severe psychiatric illness

Pairs well with:

PT-141, Himtensity Wave Therapy (Men) or Femtensity Wave Therapy (Women), BHRT, O-Shot (Women) or P-Shot (Men)

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PT 141 Peptide

PT-141 was developed for its aphrodisiac effects. This peptide has been shown to have a substantial effect on libido, generating sexual arousal in both men and women within minutes of administration. It has been shown to be effective in treating erectile dysfunction, even in men who have not responded to other ED treatments, such as Viagra. This peptide is also able to cross the blood-brain-barrier, bypassing the vascular system and acting at the level of the central nervous system, often offering less side effects than traditional ED therapies. This peptide can be administered as a nasal spray, making its use convenient and discreet.

Potential Benefits:

  • Increased satisfaction with sexual arousal level
  • Improve erectile dysfunction in men
  • Decrease in premature ejaculation
  • Help treat sexual arousal disorder in women

Potential Side Effects:

  • Nausea lasting up to 30 minutes
  • Vomiting
  • Flushing
  • Increase in blood pressure
  • Hyper libido
  • Long-lasting erections
  • Headaches
  • Increased tanning
  • Hives

Contradictions:

    • Pregnancy and breastfeeding

Pairs well with:

Oxytocin, Himtensity Wave Therapy (Men), Femtensity Wave Therapy (Women), BHRT

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Rapamycin

Rapamycin may help improve overall health and longevity. It is a peptide that was discovered as a byproduct produced by bacteria in the soil on Easter Island and was found to kill fungi. Eventually, its ability to inhibit the growth of all eukaryotic cells was also uncovered. It was found that Rapamycin targets a specific protein in cells that is responsible for metabolism and cell growth.

Potential Benefits:

  • Improved Cognition
  • Improved Cardiovascular function
  • Boost Immune System
  • Improved Renal Function
  • Improved cell health
  • Improved intestinal function

Potential Side Effects:

  • Hives or possible allergic reaction
  • Nausea/Diarrhea
  • Sore Throat
  • Dizziness
  • Lack of Appetite
  • Mouth Sores

Contradictions:

    • Pregnancy and breastfeeding

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Selank

Selank helps to enhance mood,  improve sleep, promote relaxation and works as an immune modulator. While traditionally used for mood enhancement, it has been effective in many other treatments related to immune health, anticoagulation, stress, attention issues and metabolic syndromes. Selank also has nootropic action which helps with memory and learning. Clinical studies show the result of use is similar to that of low dose tranquilizers without the side effects (withdrawal or dependence). Additionally, it has been shown to help with unwanted weight gain and lowers blood sugar levels.

Potential Benefits:

  • Improved cognition
  • Improved anxiety by increasing GABA (gamma aminobutyric acid) our “relaxation” neurotransmitter
  • Boosts the immune system
  • Improved sleep balance and quality
  • Reduces effects of chronic stress
  • May help regulate blood sugar levels
  • Elevates brain derived neurotrophic factors (vital for memory & learning)
  • Regulates inflammation
  • Anti ulcer and promotes gut mucosal barrier
  • Supports antiviral immune function

Potential Side Effects:

  • Hives or possible allergic reaction
  • Excess use can lead to desensitization

Contraindications: 

  • Pregnancy and breastfeeding

Pairs well with:

Semax, Thymosin Beta 4, Thymosin Alpha 1, Procaine Therapy

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Semaglutide

Semaglutide helps to curb your appetite, encourages weight loss and helps to control blood sugar.  It was first developed to control glycemic levels in patients with type 2 diabetes, with further studies it was shown to have significant weight loss benefits.  Semaglutide works by simulating a hormone called glucagon-like peptide-1 (GLP-1) that targets areas of the brain that regulate appetite and food intake. Our office offers a full program that combines the peptide with personal wellness coaching, providing you with the best tools to be successful in your wellness journey. AB Modern Day Warrior Semaglutide Weight Loss Program combines Semaglutide Peptide Therapy with a balanced diet and an exercise guide that focuses on efficient and healthy options.

Potential Benefits:

  • Promotes weight loss
  • Reduces appetite
  • Improves HbA1C
  • Improves PCOS symptoms
  • Lowers inflammation
  • Reduction in cardiovascular event risk in patients with diabetes
  • Reduces sugar cravings

Potential Side Effects:

  • Nausea and vomiting
  • Abdominal pain
  • Diarrhea
  • Constipation
  • Pancreatitis
  • Gallstones
  • Hypersensitivity reaction (allergic reaction, hives, redness at injection site, lip swelling)

Contraindications: 

  • Pregnancy and breastfeeding
  • Patients with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome Type 2, Type 1 Diabetes
  • Caution for patients with kidney disease (elevated creatinine low GFR) or history of pancreatitis.

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Semax

Semax was originally developed to help with circulatory issues, but it was found to work exceptionally well as a cognitive, immune, and nervous system enhancer.  It has been reported to induce the “good parts” of stress, enhancing performance without the anxiety.  It works as a melanocortin which is why it has positive effects on the immune system, gut, and nervous systems.

Potential Benefits:

  • Improved cognition
  • Improved mood
  • ADHD benefits (improves focus)
  • Boosts immune system
  • Reduces impact of chronic stress by improving stress resilience
  • Stimulates operative memory & attention
  • Elevates brain derived neurotrophic factors (vital for memory & learning)
  • Antioxidant properties
  • Boosts confidence & well being
  • Protects neurons & supports neuronal healing

Potential Side Effects:

  • Hives or possible allergic reaction
  • Excess use can lead to desensitization

Contraindications: 

  • Pregnancy and breastfeeding

Pairs well with:

Selank, Dihexa, Sermorelin, Synapsin, NAD+ Therapy, Procaine Therapy

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Tesamorelin and Ipamorelin Combination

Tesamorelin and Ipamorelin both work to release growth hormone. Specifically, they work on receptors in the pituitary to increase our own production of growth hormone.

Potential Benefits:

  • Increased muscle growth
  • Increased fat loss VAT (visceral adipose tissue)
  • Increased cellular repair and regeneration
  • Increased collagen production
  • Increased bone mineral content
  • Reduction in triglyceride levels
  • Reduced carotid intima media thickness
  • Improves cognition in patients over 60

Potential Side Effects:

  • Hives
  • Redness at injection side
  • Difficulty sleeping (switch to a.m. dose)
  • Flushing in about 30% of patients w/first injection, could be every time

Contradictions:

  • Will not be prescribed for patients with a history of any form of cancer
  • Pregnancy and breastfeeding

Pairs well with:

Sermorelin, NAD+ Therapy, Tesofensine, AB Modern Day Warrior Program (Semaglutide)

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Tesofensine Peptide

Tesofensine helps to effectively shed those unwanted pounds. It has shown great results without many of the side effects, or risks, of other more commonly prescribed weight loss medications. 

Potential Benefits:

  • Suppresses appetite
  • Improves body composition
  • Beneficial effects on cognition (particularly in learning & memory)
  • Sustained treatment increases BDNF levels in the brain & could have an antidepressant effect
  • Enhances mood
  • Promotes weight loss (in combination w/ diet & exercise)

Potential Side Effects:

  • Dry mouth
  • Difficulty sleeping
  • Feeling anxious (typically with higher doses)
  • Increase in blood pressure
  • Serotonin syndrome if combined with anti-depressant or anti-anxiety medications

Contradictions:

  • Pregnancy and breastfeeding
  • Will not be prescribed for patients currently on certain medications (including psychiatric medication)
  • Patients with uncontrolled blood pressure

Pairs well with:

Lipo Mino Injections, NAD+ Therapy, 5 Amino 1MQ, AB Modern Day Warrior Program (Semaglutide)

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Treatments that pair well with Peptide Therapy

Paired Treatments

Pairing treatments can get you dramatic results

Combining treatments can be the answer to getting the most out of your Peptide Therapy in Cincinnati, Ohio. Depending on your goals, sometimes other treatments may be needed to optimize overall quality of life. When you pair Peptide Therapy with treatments in our practice, you can get results that last longer or occur more quickly than stand alone treatments. When you come in for your consultation, your provider can speak to you about combining your treatments.

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