Peptide Therapy

balance human growth hormone levels

Peptide therapy is a way to reduce the symptoms and discomfort associated with decreased amino acid production. In addition to balancing Human Growth Hormone levels, peptide therapy also addresses a wide variety of conditions. Treatment plans can optimize your body composition, sexual health, and overall well-being.

what is peptide therapy?

 

A peptide is a short chain of amino acids that are linked together and can be thought of as a small protein. To date, over 7,000 naturally-occurring peptides have been identified. In our bodies, these small proteins typically act as signaling molecules. They bind to receptors on the cell surface and tell other cells and molecules what to do.

Peptide therapy, or the use of specific peptides in treatment, has gained great popularity in recent years. This is due largely to the fact that these peptides are highly specific (i.e., only do what you want them to do)

 

while also being well-tolerated and safe. As of January 2015, there were over 60 US FDA-approved peptide medications, 140 peptide drugs being evaluated in clinical trials, and 500 in pre-clinical development.

Most of these peptide drugs are administered via subcutaneous injections, but can also come in the form of transdermal creams, nasal sprays, and oral tablets.

what conditions does peptide therapy address?

Because these peptides are so numerous and variable in structure, their effects are likewise varied and wide-ranging. One class of these peptides are known as growth hormone secretagogues, and cause the secretion of one’s own, natural human growth hormone (hGH) in the body. These peptides have been shown to be very useful in the treatment of age-related conditions, osteoporosis, obesity, and various chronic inflammatory diseases, and have several advantages over traditional hGH administration.

Another type of peptide drug is composed of part of the hGH molecule that is responsible for fat cell death, and has been shown to be very effective as an anti-obesity drug. In addition to decreasing inflammation, these drugs lead to increased lean muscle mass and decreased body fat.

A certain class of peptide drug has been used to help prevent skin cancer by increasing the melanin in one’s skin, causing a darkening effect that mimics a quality sun tan. This peptide has also been shown to increase lean muscle mass and improve sex drive.

would you benefit from peptide therapy?

Peptide therapy encompasses numerous different drugs with varied effects, ranging from immune modulation and tissue repair to fat loss and muscle building. To find out if peptide therapy is right for you, ask your provider at your next visit.

The following peptide therapies are currently being offered at Amy Brenner, MD & Associates.

CJC 1295 + Ipamorelin

CJC-1295 + Ipamorelin is the latest in growth hormone peptide combinations. Benefits include longer binding time to growth hormone receptors, no risk of receptor saturation, none of the side effects of earlier peptides, and a strong safety & efficacy profile.

POTENTIAL BENEFITS

  • Increased muscle growth
  • Increased fat loss
  • Increased cellular repair and regeneration
  • Increased collagen production
  • Increased bone mineral content
  • Promotes slow wave deep sleep which is responsible for the highest level of muscle growth and memory retention and rejuvenation

POTENTIAL SIDE EFFECTS

  • Hives
  • Redness at injection side
  • Vivid dreams
  • Difficulty sleeping (switch to a.m. dose)
  • Flushing in about 30% of patients w/first injection, could be every time

CONTRAINDICATIONS

CJC 1295 + Ipamorelin will not be prescribed for patients with a history of any form of cancer.

Research:

Prolonged Stimulation of Growth Hormone (GH) and Insulin-Like Growth Factor I Secretion by CJC 1295, a Long-Acting Analog of GH-Releasing Hormone, in Healthy Adults

PT 141

PT 141 was developed for its aphrodisiac effects. This peptide has been shown to have a substantial effect on libido, generating sexual arousal in both men and women within minutes of administration. It has been shown to be effective in treating erectile dysfunction, even in men who have not responded to other ED treatments, such as Viagra. This peptide is also able to cross the blood-brain-barrier, bypassing the vascular system and acting at the level of the central nervous system. This property gives PT 141 an advantage over traditional ED drugs, which can decrease blood pressure to dangerous levels. This peptide can be administered as a nasal spray, making its use convenient and discreet.

POTENTIAL BENEFITS

  • Among women who attempted sexual intercourse within 24 hours after treatment, significantly more were satisfied with their level of sexual arousal following PT 141 compared with placebo.
  • Effects may be felt up to 12 hours from the time of administration and have been known to last for up to 3 days, diminishing each day
  • PT 141 has been shown to have significant results on male test patients, with what is described as “intense” and “frequent” erections lasting between 2-6 hours

 

  • For women, sexual arousal has been experienced in a varied range of minutes to weeks
  • Effective in treating sexual dysfunction in men – impotence / erectile dysfunction and premature ejaculation
  • Effective in treating sexual dysfunction in women – sexual arousal disorder
  • Does not act upon the vascular system
  • Increases sexual desire via the central nervous system

POTENTIAL SIDE EFFECTS

  • Nausea lasting up to 30 minutes
  • Vomiting
  • Flushing
  • Increase in blood pressure
  • Hyper libido
  • Long-lasting erections
  • Headaches
  • Increased tanning
  • Hives

CONTRAINDICATIONS

None

SARM LGD 4033

SARM’s are Selective Androgen Receptor Modulators. Androgens are naturally occurring hormones—such as testosterone—that regulate the development and maintenance of male sex characteristics. SARM’s provide the benefits of anabolic steroids (i.e., increased muscle mass/strength, fat loss, increased bone density, increased libido) without the quantity and/or severity of unwanted effects. SARM 4033 is administered orally and is not toxic to the liver, separating it from most oral steroids and making it an attractive treatment option to those looking to benefit from anabolic steroid drugs.

POTENTIAL BENEFITS

  • Provides benefits of anabolic/androgenic steroids such as testosterone
  • Increased fat loss
  • Increased lean muscle mass
  • Increased bone density

 

  • Fewer side effects compared to steroids, including prostate and cardiovascular outcomes
  • Not liver toxic like other oral steroids
  • Anabolic effect noted to be similar to testosterone

potential side effects

None documented

Research

J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):87-95. doi: 10.1093/gerona/gls078. Epub 2012 Mar 28.

Thymosin Beta 4

Thymosin beta 4 (TB4) is the predominant form of thymosin in our bodies. It has been found in high concentrations in wound tissue and certain blood cells involved in clotting, signifying its important role in the healing process. In fact, recent studies have revealed that the first gene to be up-regulated after an injury is the TB4 gene. As the body begins the recovery process, TB4 aids in the creation of new vessels in the injured area, which carry blood, nutrients, and repairing substances to the site. TB4 also has anti-inflammatory properties, and works to decrease the amount of inflammatory substances, called cytokines. Inflammation plays a large role in many of the symptoms associated with a large number of conditions (i.e., Lyme disease, Chronic Fatigue Syndrome, Fibromyalgia, autoimmune diseases, infections, etc.), making the potential impact of TB4 quite extensive.

The discovery of the role of TB4 in the process of immune regulation has lead to its use as a valuable therapeutic agent. TB4 has been used in the treatment of HIV, AIDS, Influenza, colds, and various infections. It has been utilized in the management of various inflammatory conditions, as well as part of treatment following heart attack due to its cardio and neuro-protective effects.

TB4 is very well tolerated and has not been found to cause any significant side effects. It can be taken on its own or in conjunction with an existing therapy, making it a versatile and valuable drug.

POTENTIAL BENEFITS

  • Calms muscle spasm
  • Improved muscle tone
  • Increased exchange of substances between cells
  • Encourages tissue repair
  • Stretches connective tissue
  • Helps maintain flexibility
  • Reduced inflammation of tissue in joints
  • Encourages the growth of new blood cells in tissue
  • Increased endurance and strength
  • Prevents the formation of adhesions and fibrous bands in muscles, tendons, and ligaments
It's simple— identify the problem areas of your body and we will recommend the right treatment plan for you.